At Woodlands OBGYN Associates we are here to help you explore your genetic testing options. Testing may be right for some but not right for others. The decision to test or not is an individual and personal decision based on many factors. Our goal is to educate you about your options and help you make the best decision for you, your pregnancy and your family. Testing for any of these genetic issues is completely optional and is your decision.
There are two types of genetic testing – Chromosomal Testing and Carrier Testing.
Carrier testing is bloodwork that determines if you are a carrier of one or more autosomal recessive or X- linked genetic conditions. There are several genetic conditions that can be passed from you to your child through DNA. People can be carriers of these genetic conditions even if there is no family history and even if they have previously had healthy children. The carrier testing, we use at Woodlands OBGYN Associates is called Inheristest or Horizon. We will give you a packet of information about this testing.
Inheritest can test for up to 144 genetic conditions. Inheritest offers 5 different panels depending on the amount of conditions you want to test for. For example, the “Inheritest core panel” tests for only the 3 most common carrier tests - Cystic Fibrosis, Fragile X, and Spinal Muscular Atrophy.
Chromosomal disorders may be caused by a missing, damaged, or extra chromosome. Most children with chromosomal disorders will have physical and/or cognitive deficits. The risk of having a baby with a chromosomal disorder increases with maternal age.
|Age||Down Syndrome||Any Chromosomal Disorder|
|20||1/1,667 - 1/526|
|25||1/1,250 - 1/476|
|30||1/952 - 1/385|
|35||1/378 - 1/192|
|40||1/106 - 1/66|
The purpose of testing is to determine if you are at increased risk of having a baby with chromosomal abnormalities. Both testing options have false-positive and false-negative results.
Options for Chromosomal Testing:
Invasive Prenatal Testing
Amniocentesis or Chorionic Villus Sampling (CVS) – These tests are invasive and involve inserting a needle into the uterus to obtain a sample of the amniotic fluid, or biopsy of the placenta. These tests will look at all of the chromosomes and provide a definitive answer, but there is a miscarriage risk associated with these tests.
Non-Invasive Prenatal Testing (NIPT)
This test consists of blood work done at the end of the first trimester and it looks at fetal DNA in your bloodstream. This test will determine if you are high risk or low risk for the three most common chromosomal abnormalities: Down Syndrome (Trisomy 21), Trisomy 18, and Trisomy 13. This test can also determine the gender of your baby.
The NIPT we use at Woodlands OBGYN Associates is called MaterniT 21 or Panorama. We will give you a packet of information about this test.
If you decide you want to have NIPT testing done or carrier testing done your next step is to call or fill out online forms at interatedgenetics.com/transparency or phone 844-799-3243 to determine your billing options.